RT Journal Article SR Electronic T1 Management of pituitary incidentalomas JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 129 OP 134 DO 10.7861/clinmed.2023-0020 VO 23 IS 2 A1 Samuel J Westall A1 Ei Thuzar Aung A1 Helmine Kejem A1 Christina Daousi A1 Sravan K Thondam YR 2023 UL http://www.rcpjournals.org/content/23/2/129.abstract AB Pituitary incidentalomas are common findings with increasing use of modern neuroradiological imaging undertaken for symptoms unrelated to pituitary disease. The prevalence of these lesions is ∼10% in autopsy studies and the incidence varies from 10% to 38% on magnetic resonance imaging in the published literature. They are almost always benign in nature and most are non-functioning (non-secreting) adenomas. Although many individuals are asymptomatic at diagnosis, some with functioning (secreting) pituitary adenomas or larger non-functioning adenomas have symptoms. All identified cases should have a thorough clinical and endocrinological evaluation to help with precise management, which depends on the size of the lesion, hormonal status (functioning versus non-functioning adenoma) and the presence of visual deficits resulting from optic nerve compression by the pituitary adenoma. Here, we provide an overview of the initial assessment and management of pituitary incidentalomas for clinicians not routinely involved in the management of pituitary disease.