RT Journal Article SR Electronic T1 Chorea JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 188 OP 189 DO 10.7861/clinmedicine.9-2-188 VO 9 IS 2 A1 Michele TM Hu A1 Richard Butterworth A1 Gavin Giovannoni A1 Andrew Church A1 Stephen Logsdail YR 2009 UL http://www.rcpjournals.org/content/9/2/188.abstract AB Two weeks after starting the oral contraceptive pill, a 16-year-old girl developed increasingly violent chorea and an evolving psychosis with prominent hallucinations, ideas of reference, and paranoia. An erythematous skin rash subsequently developed and Sydenham's chorea (SC) was diagnosed. Following neuroleptic medication and steroids, her chorea and psychosis subsided. This case illustrates that severe psychotic features can occur in SC. It is recommended that antistreptolysin O titres and antibasal ganglia antibodies are checked early in patients with evolving movement disorders and prominent neuropsychiatric features, as the window for modifying the course of this immune-mediated disorder may be narrow.