PT - JOURNAL ARTICLE AU - Adrian Baker AU - Katharine Young AU - Jonathan Potter AU - Ira Madan TI - A review of grading systems for evidence-based guidelines produced by medical specialties AID - 10.7861/clinmedicine.10-4-358 DP - 2010 Aug 01 TA - Clinical Medicine PG - 358--363 VI - 10 IP - 4 4099 - http://www.rcpjournals.org/content/10/4/358.short 4100 - http://www.rcpjournals.org/content/10/4/358.full SO - Clin Med2010 Aug 01; 10 AB - The development of evidence-based guidelines requires scrupulous attention to the method of critical appraisal. Many critical appraisal systems give ‘gold standard’ status to randomised controlled trials (RCTs) due to their ability to limit bias. While guidelines with a prominent research base consisting of RCTs have been well served by such systems, specialist societies with research bases consisting of a wide range of study designs have been at a disadvantage, potentially leading to inappropriately low grades being given for recommendations. A review of the Scottish Intercollegiate Guidelines Network, the Grading of Recommendations Assessment, Development and Evaluation, the Graphic Appraisal Tool for Epidemiology and the National Service Framework for Long Term Conditions grading systems was therefore undertaken. A matrix was developed suggesting the optimum grading system for the type of guideline being developed or question being addressed by a specialist society.