PT  - JOURNAL ARTICLE
AU  - Christopher P Derry
AU  - Mark D Wilkie
AU  - Rustam Al-Shahi Salman
AU  - Richard J Davenport
TI  - Autoimmune limbic encephalitis
AID  - 10.7861/clinmedicine.11-5-476
DP  - 2011 Oct 01
TA  - Clinical Medicine
PG  - 476--478
VI  - 11
IP  - 5
4099  - http://www.rcpjournals.org/content/11/5/476.short
4100  - http://www.rcpjournals.org/content/11/5/476.full
SO  - Clin Med2011 Oct 01; 11
AB  - Autoimmune limbic encephalitis is an increasingly recognised cause of cognitive decline and confusion. The typical presentation is with subacute cognitive decline, behavioural disturbance and seizures. Magnetic resonance imaging may show characteristic changes in the medial temporal regions. The diagnosis is confirmed by identification of elevated voltage-gated potassium channel antibody (VGKC-Ab) titres. It is a highly treatable condition, often responding well to intravenous immunoglobulin or steroids. Recognition of autoimmune limbic encephalitis is sometimes delayed–usually because the diagnosis has not been considered–which can result in long-term neurological consequences.