PT - JOURNAL ARTICLE AU - Keng Ngee Hng AU - Yeng S Ang TI - Overview of bariatric surgery for the physician AID - 10.7861/clinmedicine.12-5-435 DP - 2012 Oct 01 TA - Clinical Medicine PG - 435--440 VI - 12 IP - 5 4099 - http://www.rcpjournals.org/content/12/5/435.short 4100 - http://www.rcpjournals.org/content/12/5/435.full SO - Clin Med2012 Oct 01; 12 AB - The worldwide pandemic of obesity carries alarming health and socioeconomic implications. Bariatric surgery is currently the only effective treatment for severe obesity. It is safe, with mortality comparable to that of cholecystectomy, and effective in producing substantial and sustainable weight loss, along with high rates of resolution of associated comorbidities, including type 2 diabetes. For this reason, indications for bariatric surgery are being widened. In addition to volume restriction and malabsorption, bariatric surgery brings about neurohormonal changes that affect satiety and glucose homeostasis. Increased understanding of these mechanisms will help realise therapeutic benefits by pharmacological means. Bariatric surgery improves long-term mortality but can cause long-term nutritional deficiencies. The safety of pregnancy after bariatric surgery is still being elucidated.