RT Journal Article SR Electronic T1 Fever of unknown origin as the first manifestation of colonic pathology JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 141 OP 145 DO 10.7861/clinmedicine.13-2-141 VO 13 IS 2 A1 Moncef Belhassen-García A1 Virginia Velasco-Tirado A1 Amparo López-Bernus A1 Montserrat Alonso-Sardón A1 Adela Carpio-Pérez A1 Lucía Fuentes-Pardo A1 Javier Pardo-Lledías A1 Lucia Alvela-Suárez A1 Ángela Romero-Alegría A1 Alicia Iglesias-Gomez A1 Miguel Cordero Sánchez YR 2013 UL http://www.rcpjournals.org/content/13/2/141.abstract AB Fever of unknown origin (FUO) is an entity caused by more than 200 diseases. Haematologic neoplasms are the most common malignant cause of FUO. Fever as a first symptom of colonic tumour pathology, both benign and malignant, is a rare form of presentation. Our work is a descriptive study of a series of 23 patients with colonic tumoral pathology who presented with fever of unknown origin. The mean age was 67.6 years; 56.5% of patients were men and 43.5% were women. Primary malignant neoplasia was the most common diagnosis. Blood cultures were positive in 45% of the samples. Coagulase-negative staphylococci were the most common cause of bacteraemia. Nine of 10 faecal occult blood tests performed were positive. Fever secondary to colon neoplasms, both benign and malignant, usually presents with a bacteraemic pattern, with positive results for blood-culture tests in a high percentage of cases.