RT Journal Article SR Electronic T1 Cardiac disease in pregnancy JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 553 OP 560 DO 10.7861/clinmedicine.12-6-553 VO 12 IS 6 A1 Surabhi Nanda A1 Catherine Nelson-Piercy A1 Lucy Mackillop YR 2012 UL http://www.rcpjournals.org/content/12/6/553.abstract AB Cardiac disease is the leading cause of maternal mortality in the UK. The major causes of cardiac deaths in pregnancy include cardiomyopathy, myocardial infarction, ischaemic heart disease and dissection of the thoracic aorta. With increasing numbers of migrant women in the UK, rheumatic heart disease in pregnancy has also re-emerged. Women with uncorrected congenital heart disease and those who have undergone corrective or palliative surgery may have complicated pregnancies. Women with metal prosthetic valves face difficult decisions regarding anticoagulation in pregnancy and have an increased risk of haemorrhage. Not all women with significant heart disease are able to meet the increased physiological demands of pregnancy. The care of pregnant women with heart disease thus requires a multidisciplinary approach, involving obstetricians, cardiologists and anaesthetists. This allows appropriate surveillance of maternal and fetal well-being, as well as planning and documentation of the management of elective and emergency delivery. This review discusses common cardiac conditions encountered in pregnancy and their antenatal and intrapartum management.