PT  - JOURNAL ARTICLE
AU  - Chun Yang
AU  - Hanbin Li
AU  - Zhihai Wang
AU  - Wanying Zhang
AU  - Kun Zhou
AU  - Jianhua Meng
AU  - Ying Zhao
AU  - Jing Pan
AU  - Xiaofeng Lv
AU  - Hongyan Liang
AU  - Xiaofeng Jiang
TI  - Glycated albumin is a potential diagnostic tool for diabetes mellitus
AID  - 10.7861/clinmedicine.12-6-568
DP  - 2012 Dec 01
TA  - Clinical Medicine
PG  - 568--571
VI  - 12
IP  - 6
4099  - http://www.rcpjournals.org/content/12/6/568.short
4100  - http://www.rcpjournals.org/content/12/6/568.full
SO  - Clin Med2012 Dec 01; 12
AB  - Using a community-based population cross-sectional study, we investigated the validity of an enzymatic method for glycated albumin (GA) measurements and evaluated its utility as a diagnostic tool for diabetes mellitus (DM). In total, 1,211 participants from the city of Harbin, People's Republic of China, were enrolled in the study. A receiver operating characteristic (ROC) analysis for GA, fasting plasma glucose (FPG) and haemoglobin A1c (HbA1c) measurements in diagnosed and undiagnosed DM were compared, based on a definition of DM using 1999 WHO criteria. We also estimated the correlation among GA, HbA1c and other clinical characteristics. Significant and positive correlations of fasting serum GA with FPG (r 50.8097) and HbA1c (r 50.8976) were found in participants enrolled in the study. ROC analysis for GA predicting undiagnosed DM with a cut-off point of 15.7% was similar to that of FPG and HbA1c. Therefore, our data indicate that GA is a potential tool for DM diagnosis.