RT Journal Article SR Electronic T1 Legal and ethical implications of NICE guidance aimed at optimising organ transplantation after circulatory death JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 340 OP 343 DO 10.7861/clinmedicine.13-4-340 VO 13 IS 4 A1 Samuel Littlejohns A1 Holly Bontoft A1 Peter Littlejohns A1 Judith Richardson A1 Alistair Robertson YR 2013 UL http://www.rcpjournals.org/content/13/4/340.abstract AB Increasing the number of organ transplants is a priority for most governments. While potential new legislation for donor registration, such as the Welsh Government white paper on establishing an opt-out system for Welsh residents, is the focus of most ethical and legal scrutiny, there are also other approaches to increase the number of patients receiving organ transplants. The then National Institute for Health and Care Excellence (NICE) published guidance on this issue in 2011, but subsequent debate in this journal has suggested that the guidance was presumptuous and might encourage unethical practice. This paper addresses these concerns and concludes that the NICE guidance provides a legal, ethical and clinically relevant way forward in a complex and developing public health issue.