RT Journal Article SR Electronic T1 Connective tissue disease in pregnancy JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 580 OP 584 DO 10.7861/clinmedicine.13-6-580 VO 13 IS 6 A1 Oier Ateka-Barrutia A1 Catherine Nelson-Piercy YR 2013 UL http://www.rcpjournals.org/content/13/6/580.abstract AB Connective tissue diseases (CTD) include a variety of chronic multisystem disorders with a high percentage of autoimmune conditions. Many of these conditions affect women of childbearing age and, therefore, pregnancy poses an important challenge for doctors looking after such women. Knowledge of medication safety, the effect of pregnancy on such diseases and vice versa, together with preconception counselling and multidisciplinary team care, are the basic pillars needed to provide the best obstetric and medical care to these women. In this review, we discuss the management of the most common autoimmune CTD before, during and after pregnancy, along with the most relevant issues regarding appropriate medication.