PT - JOURNAL ARTICLE AU - Vinit Sawhney AU - Oksana Maksunova AU - Syed Ahsan AU - Muhiddin Ozkor AU - Mark Westwood TI - Lesson of the month 1: Pericardial mass and cardiac tamponade associated with <em>Mycoplasma pneumoniae</em> AID - 10.7861/clinmedicine.14-5-549 DP - 2014 Oct 01 TA - Clinical Medicine PG - 549--551 VI - 14 IP - 5 4099 - http://www.rcpjournals.org/content/14/5/549.short 4100 - http://www.rcpjournals.org/content/14/5/549.full SO - Clin Med2014 Oct 01; 14 AB - Mycoplasma pneumoniae primarily causes respiratory tract infections. Extrapulmonary manifestations are seen in 20–25% of cases. Cardiac involvement is rarely reported. We present a unique case of a pericardial mass and cardiac tamponade associated with a Mycoplasma pneumoniae pneumonia. This required emergency pericardial fenestration. The patient improved dramatically postoperatively on antibiotics and there was no recurrence of the pericardial effusion on follow up. This case highlights the often forgotten invasive properties of a common respiratory tract pathogen and emphasises the need to consider this easily treatable entity in the differential diagnosis of idiopathic pericardial effusions.