PT - JOURNAL ARTICLE AU - Deepak Joshi AU - Rolf Jager AU - Steven Hurel AU - Stephen P Pereira AU - Gavin J Johnson AU - Michael Chapman AU - Robert Fowler AU - Alison Winstanley AU - Nicholas Losseff AU - George JM Webster TI - Cerebral involvement in IgG4-related disease AID - 10.7861/clinmedicine.15-2-130 DP - 2015 Apr 01 TA - Clinical Medicine PG - 130--134 VI - 15 IP - 2 4099 - http://www.rcpjournals.org/content/15/2/130.short 4100 - http://www.rcpjournals.org/content/15/2/130.full SO - Clin Med2015 Apr 01; 15 AB - IgG4-related disease is a recently recognised multi-system disease. Common organ involvement includes the pancreas, biliary tree and salivary glands. Central nervous system involvement has been infrequently reported. In a single-centre cohort of 84 patients, we report cerebral involvement in three (4%) patients. Details of cerebral involvement in these patients are outlined, including pituitary involvement in two patients and a diffuse autoimmune-like encephalopathy in the other.