RT Journal Article SR Electronic T1 Implementation of NICE clinical guideline 95 on chest pain of recent onset: experience in a district general hospital JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 225 OP 258 DO 10.7861/clinmedicine.15-3-225 VO 15 IS 3 A1 Julian OM Ormerod A1 Caroline Wretham A1 Andy Beale A1 Douglas Haynes A1 Iwan Harries A1 Steve Ramcharitar A1 Paul W Foley A1 William A McCrea A1 Badri Chandrasekaran A1 Edward Barnes YR 2015 UL http://www.rcpjournals.org/content/15/3/225.abstract AB The National Institute for Health and Care Excellence (NICE) CG95 clinical guideline on chest pain of recent onset was published in 2010. There is debate over whether the proposed strategy improves patient care and its implications on service costs. Following a six-month pilot, 472 consecutive patient records were audited for pre-test probability of significant coronary artery disease, investigations performed and outcomes. Low- and moderate-risk patients had an unexpectedly low rate of coronary disease and revascularisation. Computerised tomography coronary angiography (CTCA) and stress echocardiography performed similarly, though the latter was more resource intensive. High-/very high-risk patients frequently required revascularisation and greater than 10% of each group had prognostically significant disease, going against the recommendation that very high risk patients do not undergo angiography. There were frequent protocol deviations and training clinic staff in the new approach was challenging. In conclusion, implementing NICE CG95 is feasible but presents challenges. Staff require training to follow the protocol consistently. Functional testing had no benefits over anatomical testing with CTCA, which may allow cost savings in some departments.