PT - JOURNAL ARTICLE AU - Vanessa Foggo AU - Jamie Cavenagh TI - Malignant causes of fever of unknown origin AID - 10.7861/clinmedicine.15-3-292 DP - 2015 Jun 01 TA - Clinical Medicine PG - 292--294 VI - 15 IP - 3 4099 - http://www.rcpjournals.org/content/15/3/292.short 4100 - http://www.rcpjournals.org/content/15/3/292.full SO - Clin Med2015 Jun 01; 15 AB - The presence of fever in malignancy usually indicates infection, though transfusion, thrombosis and drugs are also culprits. However, particularly in some tumour types, fever can also be a paraneoplastic syndrome, caused by the malignancy itself. This can be a difficult diagnosis to establish and presents a therapeutic challenge to the physician when the underlying malignancy is not easily treated.