RT Journal Article SR Electronic T1 Writing clinical scenarios for clinical science questions JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 142 OP 145 DO 10.7861/clinmedicine.16-2-142 VO 16 IS 2 A1 Phil EM Smith A1 John C Mucklow YR 2016 UL http://www.rcpjournals.org/content/16/2/142.abstract AB Written knowledge assessments for physicians in training typically involve multiple-choice questions that use a clinical scenario in a single-best-answer format. The Royal College of Physicians Part 1 MRCP(UK) examination includes basic sciences themes that are challenging to assess through a clinical scenario. A realistic clinical setting based on everyday clinical practice and integral to the question is the clearest demonstration that the knowledge being assessed is clinically relevant. However, without special attention to detail, the scenario in a clinical science question can appear redundant or artificial. Reading unnecessary material frustrates candidates and threatens the reputation of the assessment. In this paper we discuss why a clinical scenario is important for basic science questions and offer advice on setting realistic and plausible clinical scenarios for such questions.