RT Journal Article SR Electronic T1 The importance of interactions between atrial fibrillation and heart failure JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 272 OP 276 DO 10.7861/clinmedicine.16-3-272 VO 16 IS 3 A1 Muhammad A Khan A1 Duwarakan K Satchithananda A1 Mamas A Mamas YR 2016 UL http://www.rcpjournals.org/content/16/3/272.abstract AB Heart failure (HF) and atrial fibrillation (AF) are among the commonest cardiovascular conditions encountered in clinical practice and frequently coexist. Over the last decade, they have evolved into global cardiovascular epidemics. This, in turn, has huge clinical and economic implications. There is ample evidence that AF and HF have a mutually deleterious effect on each other. AF is not only a marker of HF severity but also affects HF prognosis independently. This article presents the close pathophysiological relationship between AF and HF and the adverse prognostic consequences of this bidirectional interaction. The scope of various therapeutic modalities and their potential impacts are discussed briefly.