RT Journal Article SR Electronic T1 ST elevation myocardial infarction JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 277 OP 282 DO 10.7861/clinmedicine.16-3-277 VO 16 IS 3 A1 Tawfiq Choudhury A1 Nick EJ West A1 Magdi El-Omar YR 2016 UL http://www.rcpjournals.org/content/16/3/277.abstract AB ST segment elevation myocardial infarction remains a significant contributor to morbidity and mortality worldwide, despite a declining incidence and better survival rates. It usually results from thrombotic occlusion of a coronary artery at the site of a ruptured or eroded plaque. Diagnosis is based on characteristic symptoms and electrocardiogram changes, and confirmed subsequently by raised cardiac enzymes. Prognosis is dependent on the size of the infarct, presence of collaterals and speed with which the occluded artery is reopened. Mechanical reperfusion by primary percutaneous coronary intervention is superior to fibrinolytic therapy if delivered by an experienced team in a timely fashion. Post-reperfusion care includes monitoring for complications, evaluation of left ventricular function, secondary preventive therapy and cardiac rehabilitation.