PT - JOURNAL ARTICLE AU - Alistair Connell AU - Chris Laing TI - Acute kidney injury AID - 10.7861/clinmedicine.15-6-581 DP - 2015 Dec 01 TA - Clinical Medicine PG - 581--584 VI - 15 IP - 6 4099 - http://www.rcpjournals.org/content/15/6/581.short 4100 - http://www.rcpjournals.org/content/15/6/581.full SO - Clin Med2015 Dec 01; 15 AB - Acute kidney injury (AKI) – an abrupt deterioration in renal function – causes a rise in serum creatinine (SCr) or fall in urine output. It is common, occurring in up to 20% of hospital admissions. Importantly, even small rises in SCr are associated with increased risk of death and longer hospital stays. A 2009 National Confidential Enquiry into Patient Outcome and Death report found that a proportion of AKI in secondary care was avoidable. In addition, management of established AKI was ‘good’ less than half the time. In practice, AKI represents a heterogeneous group of conditions, encompassing impairments in both kidney structure and function. Delivering disease-specific treatment early in the course of AKI may improve outcomes. The provision of best-practice care for all will rely on a better understanding of risk, and frameworks of care that can be applied across a diverse patient group.