PT - JOURNAL ARTICLE AU - James Bailey AU - Kayvan Khadjooi TI - Lesson of the month 1: Artery of Percheron occlusion – an ­uncommon cause of coma in a middle-aged man AID - 10.7861/clinmedicine.16-1-86 DP - 2016 Feb 01 TA - Clinical Medicine PG - 86--87 VI - 16 IP - 1 4099 - http://www.rcpjournals.org/content/16/1/86.short 4100 - http://www.rcpjournals.org/content/16/1/86.full SO - Clin Med2016 Feb 01; 16 AB - Bilateral paramedian thalamic infarction resulting from artery of Percheron occlusion presents with a distinct clinical syndrome comprising impaired consciousness, often with vertical gaze palsy and memory impairment. This uncommon anatomical variant arises as a single artery supplying both paramedian thalami. Early recognition can be challenging in the obtunded patient, where the differential diagnosis is broad. The acute physician should consider this diagnosis in a patient presenting with unexplained coma so that emergent treatments such as thrombolysis can be employed. Early imaging with computerised tomography can often be normal; therefore the use of magnetic resonance imaging is essential in confirming the diagnosis.