PT - JOURNAL ARTICLE AU - Richard Conway AU - Carl Orr AU - Geraldine M McCarthy TI - Lesson of the month 1: Septic arthritis with normal acute phase reactants and white cell count in a patient receiving tocilizumab AID - 10.7861/clinmedicine.17-3-280 DP - 2017 Jun 01 TA - Clinical Medicine PG - 280--281 VI - 17 IP - 3 4099 - http://www.rcpjournals.org/content/17/3/280.short 4100 - http://www.rcpjournals.org/content/17/3/280.full SO - Clin Med2017 Jun 01; 17 AB - Septic arthritis represents 8–27% of cases of monoarthritis presenting to the emergency department. Tocilizumab is an interleukin-6 blocking monoclonal antibody with the mechanistic potential to interfere with the body's normal inflammatory response to an infectious insult. We present a case of septic arthritis with a normal white cell count, C-reactive protein, erythrocyte sedimentation rate and fibrinogen in a patient treated with tocilizumab.