PT - JOURNAL ARTICLE AU - William Thomas AU - Mars van’t Veer AU - Martin Besser TI - Haemophagocytic lymphohistiocytosis: an elusive syndrome AID - 10.7861/clinmedicine.16-5-432 DP - 2016 Oct 01 TA - Clinical Medicine PG - 432--436 VI - 16 IP - 5 4099 - http://www.rcpjournals.org/content/16/5/432.short 4100 - http://www.rcpjournals.org/content/16/5/432.full SO - Clin Med2016 Oct 01; 16 AB - Haemophagocytic lymphohistiocytosis is a rare inflammatory condition. It can present in adult general medical patients and is a challenging diagnostic conundrum. This article provides an overview of the pathophysiology and clinical presentation of the syndrome for the general physician who will be rarely confronted with this problem but will have to act promptly when the situation arises. Treatment is also briefly discussed, although this usually occurs in a specialist setting after the diagnosis has been established.