PT  - JOURNAL ARTICLE
AU  - Kevin O’Gallagher
AU  - Evelyn Chou
AU  - Swarna Jeyabraba
AU  - Aish Sinha
AU  - Daniel Robb
AU  - Jonathan Byrne
TI  - An extreme case of platypnoea-orthodeoxia syndrome
AID  - 10.7861/clinmedicine.16-5-453
DP  - 2016 Oct 01
TA  - Clinical Medicine
PG  - 453--454
VI  - 16
IP  - 5
4099  - http://www.rcpjournals.org/content/16/5/453.short
4100  - http://www.rcpjournals.org/content/16/5/453.full
SO  - Clin Med2016 Oct 01; 16
AB  - An 80-year-old female presented with progressive breathlessness, worse on sitting or standing and relieved by lying flat. Subsequent investigations identified a patent foramen ovale (PFO) with right-to-left flow across the interatrial septum (IAS). A diagnosis of platypnoea orthodeoxia syndrome secondary to inter-atrial shunting was made. Technical features precluded a percutaneous PFO closure so an open surgical repair was performed with complete resolution of symptoms. We discuss the pathophysiology and management of platypnoea orthodeoxia syndrome.