RT Journal Article
SR Electronic
T1 Lesson of the month 2: An easily missed cause of confusion
JF Clinical Medicine
JO Clin Med
FD Royal College of Physicians
SP 491
OP 493
DO 10.7861/clinmedicine.16-5-491
VO 16
IS 5
A1 Ben Oliveira
A1 Sangita Chaterjee
A1 Aine Burns
YR 2016
UL http://www.rcpjournals.org/content/16/5/491.abstract
AB We describe the case of an 85-year-old woman who developed acute confusion, acute kidney injury and temperature spikes while on extended courses of beta-lactams for osteomyelitis. The cause of her deterioration was felt to be due to sepsis when in fact it was as a result of toxicity from antibiotics. This was demonstrated by a rapid resolution in her condition following haemodialysis. We also performed a literature review to appraise the neuro and nephrotoxicity of various antibiotics and how best to manage toxicity when it occurs.