TY - JOUR T1 - Clinical implications of the global multidrug-resistant tuberculosis epidemic JF - Clinical Medicine JO - Clin Med SP - 565 LP - 570 DO - 10.7861/clinmedicine.16-6-565 VL - 16 IS - 6 AU - Kartik Kumar AU - Ibrahim Abubakar Y1 - 2016/12/01 UR - http://www.rcpjournals.org/content/16/6/565.abstract N2 - Multidrug-resistant tuberculosis (MDR TB) is a significant threat to global health estimated to account for nearly half a million new cases and over 200,000 deaths in 2013. The number of MDR TB cases in the UK has risen over the last 15 years, with ever more complex clinical cases and associated challenging public health and societal implications. In this review, we provide an overview of the epidemiology of MDR TB globally and in the UK, outline the clinical management of MDR TB and summarise recent advances in diagnostics and prospects for new treatment. ER -