@article {Compstons121, author = {Juliet Compston}, title = {Osteoporosis: advances in risk assessment and management}, volume = {16}, number = {Suppl 6}, pages = {s121--s124}, year = {2016}, doi = {10.7861/clinmedicine.16-6-s121}, publisher = {Royal College of Physicians}, abstract = {In the past three decades, there have been major advances in our understanding of bone biology and these have been -accompanied by a significant improvement in the management of osteoporosis. Fracture risk prediction algorithms using -clinical risk factors, with or without measurement of bone mineral density, have enabled more accurate targeting of treatment and a range of cost-effective pharmacological interventions is available to reduce fracture risk. Despite these advances, a number of challenges remain. In particular, treatment rates in high-risk individuals are low and adherence to treatment is poor. Addressing this treatment gap through measures such as fracture liaison services, which provide a coordinated and cost-effective strategy for secondary fracture prevention, is an important future priority.}, issn = {1470-2118}, URL = {https://www.rcpjournals.org/content/16/Suppl_6/s121}, eprint = {https://www.rcpjournals.org/content/16/Suppl_6/s121.full.pdf}, journal = {Clinical Medicine} }