PT  - JOURNAL ARTICLE
AU  - Juliet Compston
TI  - Osteoporosis: advances in risk assessment and management
AID  - 10.7861/clinmedicine.16-6-s121
DP  - 2016 Dec 01
TA  - Clinical Medicine
PG  - s121--s124
VI  - 16
IP  - Suppl 6
4099  - http://www.rcpjournals.org/content/16/Suppl_6/s121.short
4100  - http://www.rcpjournals.org/content/16/Suppl_6/s121.full
SO  - Clin Med2016 Dec 01; 16
AB  - In the past three decades, there have been major advances in our understanding of bone biology and these have been ­accompanied by a significant improvement in the management of osteoporosis. Fracture risk prediction algorithms using ­clinical risk factors, with or without measurement of bone mineral density, have enabled more accurate targeting of treatment and a range of cost-effective pharmacological interventions is available to reduce fracture risk. Despite these advances, a number of challenges remain. In particular, treatment rates in high-risk individuals are low and adherence to treatment is poor. Addressing this treatment gap through measures such as fracture liaison services, which provide a coordinated and cost-effective strategy for secondary fracture prevention, is an important future priority.