RT Journal Article SR Electronic T1 The use of panel testing in familial breast and ovarian cancer JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 568 OP 572 DO 10.7861/clinmedicine.17-6-568 VO 17 IS 6 A1 Matina Prapa A1 Joyce Solomons A1 Marc Tischkowitz YR 2017 UL http://www.rcpjournals.org/content/17/6/568.abstract AB Advances in sequencing technology have led to the introduction of panel testing in hereditary breast and ovarian cancer. While direct-to-consumer testing services have become widely available, the clinical validity of many of the genes on panel tests remains contentious and risk management guidelines are often lacking. This article gives an overview of advantages with panel testing as well as important challenges, including clinical translation of test results.