@article {Warricker578, author = {Frazer Warricker and Zafir Islam and Benoy N Shah}, title = {Lesson of the month 1: Obesity hypoventilation (Pickwickian) syndrome: a reversible cause of severe pulmonary hypertension}, volume = {17}, number = {6}, pages = {578--581}, year = {2017}, doi = {10.7861/clinmedicine.17-6-578}, publisher = {Royal College of Physicians}, abstract = {Obesity hypoventilation syndrome (OHS) is a condition in which an individual with a body mass index \>30 kg/m2 develops daytime alveolar hypoventilation (defined as a resting PaCO2 \>45 mmHg) that cannot be attributed to other pathologies. It is a condition with increasing prevalence and rising cost to healthcare systems worldwide. Right heart failure and pulmonary hypertension are well-known complications of this syndrome. Here, we present the case of a female patient with OHS who presented to our centre with severe pulmonary hypertension, which resolved with appropriate treatment. We also review this clinical condition and its diagnosis and management.}, issn = {1470-2118}, URL = {https://www.rcpjournals.org/content/17/6/578}, eprint = {https://www.rcpjournals.org/content/17/6/578.full.pdf}, journal = {Clinical Medicine} }