PT - JOURNAL ARTICLE AU - Edwin AM Gale TI - Between two cultures: the expert clinician and the pharmaceutical industry AID - 10.7861/clinmedicine.3-6-538 DP - 2003 Nov 01 TA - Clinical Medicine PG - 538--541 VI - 3 IP - 6 4099 - http://www.rcpjournals.org/content/3/6/538.short 4100 - http://www.rcpjournals.org/content/3/6/538.full SO - Clin Med2003 Nov 01; 3 AB - Expert clinicians, valued for their academic status and independence, are used by the pharmaceutical industry for advice, for contract research, and as a means of conveying their message to other clinicians. Both academics and industry depend upon this interaction, but there is a fundamental clash of cultures at the interface between the two. Independence cannot be marketed for a fee, opinion too easily shades into advocacy, and secrecy and science do not mix. Formal guidelines and declarations of interest are inadequate as a means of policing an interface where undisclosed amounts of money change hands so freely. In the absence of effective sanctions, each of us must seek a personal solution to the professional and ethical issues involved.