PT - JOURNAL ARTICLE AU - Ruth Porther AU - Gavin Ross AU - Subramaniam Nagasayi TI - Breathlessness in liver disease: A case of hepatopulmonary syndrome  AID - 10.7861/clinmedicine.19-3-250 DP - 2019 May 01 TA - Clinical Medicine PG - 250--251 VI - 19 IP - 3 4099 - http://www.rcpjournals.org/content/19/3/250.short 4100 - http://www.rcpjournals.org/content/19/3/250.full SO - Clin Med2019 May 01; 19 AB - Hepatopulmonary syndrome (HPS) is often not considered as a cause of breathlessness in patients with liver cirrhosis. It consists of a triad of liver disease, intrapulmonary shunting and hypoxaemia. Here we discuss HPS in a patient presenting with acute on chronic breathlessness and typical features of orthodeoxia and platypnoea. Evidence of intrapulmonary shunting on imaging was essential to making the diagnosis, which carries a poor prognosis and was an urgent indication for liver transplantation.