TY - JOUR T1 - Neurosurgical grade biomaterial, DuraGen<sup>TM</sup>, offers a promising matrix for protected delivery of neural stem cells in clinical cell therapies JF - Future Healthcare Journal JO - Future Healthc J SP - 76 LP - 76 DO - 10.7861/futurehosp.6-1-s76 VL - 6 IS - Suppl 1 AU - Louise Finch AU - Christopher Adams AU - Jon Sen AU - Jacqueline Tickle AU - Nikolaos Tzerakis AU - Divya Maitreyi Chari Y1 - 2019/03/01 UR - http://www.rcpjournals.org/content/6/Suppl_1/76.abstract N2 - Transplantation of neural stem cells (NSCs) into sites of neurological injury is being investigated in clinical trials around the world. These important self-renewing and multipotent precursors can generate the major central nervous system cell types – neurons, astrocytes and oligodendrocytes, and have a major role in ‘restorative cell therapeutics’. However, high stem cell death in host tissue (&gt;∼90%) following surgical delivery procedures is a critical barrier to clinical translation. Polymer-based encapsulating biomaterials offer protective matrices to improve stem cell survival but the majority of studies use laboratory based … ER -