PT - JOURNAL ARTICLE AU - Natasha Valiallah AU - James Denny AU - Fiona Worsnop AU - Janakan Natkunarajah TI - Images of the month 3: The ‘bull's head’ sign of SAPHO syndrome AID - 10.7861/clinmedicine.19-4-342 DP - 2019 Jul 01 TA - Clinical Medicine PG - 342--343 VI - 19 IP - 4 4099 - http://www.rcpjournals.org/content/19/4/342.short 4100 - http://www.rcpjournals.org/content/19/4/342.full SO - Clin Med2019 Jul 01; 19 AB - Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a rare, chronic, inflammatory disorder with cutaneous and osteoarticular manifestations.1 The aetiology of SAPHO syndrome is unknown and therefore treatment is tailored towards the individual. Non-steroidal anti-inflammatory drugs, bisphosphonates, corticosteriods, antibiotics, disease modifying anti-rheumatic drugs and biologics have all been used with variable success.