@article {Mandal523, author = {Amit KJ Mandal and Bashir Mohamad and Constantinos G Missouris}, title = {Lessons of the month 3: Gone but not forgotten {\textendash} Osler {\textendash} a reminder of the syndrome not bearing his name}, volume = {19}, number = {6}, pages = {523--525}, year = {2019}, doi = {10.7861/clinmed.2019.0253}, publisher = {Royal College of Physicians}, abstract = {Streptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3\% of cases of native valve infective endocarditis, with mortality rates up to 60\%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as {\textquoteleft}micrococci{\textquoteright}, subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis.}, issn = {1470-2118}, URL = {https://www.rcpjournals.org/content/19/6/523}, eprint = {https://www.rcpjournals.org/content/19/6/523.full.pdf}, journal = {Clinical Medicine} }