TY - JOUR T1 - Lessons of the month 3: Gone but not forgotten – Osler – a reminder of the syndrome not bearing his name JF - Clinical Medicine JO - Clin Med SP - 523 LP - 525 DO - 10.7861/clinmed.2019.0253 VL - 19 IS - 6 AU - Amit KJ Mandal AU - Bashir Mohamad AU - Constantinos G Missouris Y1 - 2019/11/01 UR - http://www.rcpjournals.org/content/19/6/523.abstract N2 - Streptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3% of cases of native valve infective endocarditis, with mortality rates up to 60%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as ‘micrococci’, subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis. ER -