PT - JOURNAL ARTICLE AU - Mandal, Amit KJ AU - Mohamad, Bashir AU - Missouris, Constantinos G TI - Lessons of the month 3: Gone but not forgotten – Osler – a reminder of the syndrome not bearing his name AID - 10.7861/clinmed.2019.0253 DP - 2019 Nov 01 TA - Clinical Medicine PG - 523--525 VI - 19 IP - 6 4099 - http://www.rcpjournals.org/content/19/6/523.short 4100 - http://www.rcpjournals.org/content/19/6/523.full SO - Clin Med2019 Nov 01; 19 AB - Streptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3% of cases of native valve infective endocarditis, with mortality rates up to 60%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as ‘micrococci’, subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis.