PT  - JOURNAL ARTICLE
AU  - Mandal, Amit KJ
AU  - Mohamad, Bashir
AU  - Missouris, Constantinos G
TI  - Lessons of the month 3: Gone but not forgotten – Osler – a reminder of the syndrome not bearing his name
AID  - 10.7861/clinmed.2019.0253
DP  - 2019 Nov 01
TA  - Clinical Medicine
PG  - 523--525
VI  - 19
IP  - 6
4099  - http://www.rcpjournals.org/content/19/6/523.short
4100  - http://www.rcpjournals.org/content/19/6/523.full
SO  - Clin Med2019 Nov 01; 19
AB  - Streptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3% of cases of native valve infective endocarditis, with mortality rates up to 60%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as ‘micrococci’, subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis.