Table 1.

Standardised nomenclature associated with acquired acute cognitive dysfunction

NameDefinitionTime courseCause
Acute encephalopathyChange from baseline cognitive status.Rapidly developing (<4 hours).Pathobiological process in the brain.
DeliriumDisturbance in attention, cognition and awareness, not explained by another neurocognitive disorder or reduced level of arousal.Hours to few days. Tends to fluctuate.Direct physiologic consequence of another medical condition, intoxication, withdrawal, toxin exposure or multiple aetiologies.
ComaSeverely depressed responsiveness.Variable.May follow acute encephalopathy or delirium.