Table 1.

Mechanisms of hypoxaemia and clinical examples

CategoryExamples
Reduced atmospheric oxygen (patmosO2)Altitude
Alveolar hypoventilationAirways disease, neuromuscular disease etc
Pulmonary ventilation/perfusion mismatchPneumonia, pulmonary embolism etc
Diffusion limitationInterstitial oedema or inflammation
ShuntAtrial septal defect, tetralogy of Fallot etc
Reduced mixed venous oxygen (pvO2)Cardiogenic or hypovolaemic shock