Summary

What is known?
  • The average viral shedding duration is between 12 and 20 days. A number of papers demonstrate prolonged viral shedding in severe illness.

  • Most investigations were conducted in an hospital environment.

What is the question?
  • What are the special aspects of COVID-19 in home quarantine compared to hospitalised patients?

  • What is the medium for and the duration of virus shedding? Which are the main clinical characteristics? Are there differences regarding age and gender?

  • What is the frequency of recurrences or seroconversion?

What was found?
  • Further details about COVID-19 patient care in home quarantine, clinical characteristics and virus shedding duration.

  • Special difficulties from the collaboration with local authorities and psychological burdens for patients.

  • The study showed the necessity for consequent testing in order to end quarantine safely.

  • Further the investigation shed light on seroconversion and recurrences.

What is the implication for practice now?
  • Patients in home quarantine should be monitored regularly for aggravation of disease.

  • Discharge should be based on clinical and laboratory findings.

  • Faecal shedding of the virus should be investigated as it lasts longer than throat swabs and may be a source of viral spreading.

  • Besides flu-like symptoms of the upper respiratory tract, headache, anosmia and ageusia should raise awareness for COVID-19.