Common symptoms in individuals presenting with pituitary insufficiency6
| TSH | ACTH | Growth hormone | Gonadotrophin (male) | Gonadotrophin (female) |
|---|---|---|---|---|
| Lethargy/fatigue | Lethargy/fatigue | Decreased energy levels | Loss of libido | Loss of libido |
| Weakness | Weakness | Decreased wellbeing | Erectile dysfunction | Hot flushes |
| Cold intolerance | Myalgia | Decreased muscle mass and strength | Decreased muscle mass | a-/oligo-menorrhea |
| Weight gain | Weight loss | Decreased bone mass density | Decreased bone mass density | Decreased bone mass density |
| Dry skin | Nausea/vomiting | Increased body fat / obesity | Testicular atrophy | Vaginal dryness |
| Constipation | Hypoglycaemia | Increased cardiovascular risk | Loss of body hair | Breast atrophy |
| Hoarseness | Postural hypotension | Long-term insulin resistance | Gynaecomastia | Premature atherosclerosis |
ACTH = adrenocorticotropic hormone; TSH = thyroid stimulating hormone.