Cohort clinical characteristics, stratified by occurrence of serious event
| Demographic | N | Cohort (n=296) | Any event (n=133) | No event (n=163) | p |
|---|---|---|---|---|---|
| Male sex | 296 | 162 (54.7) | 76 (57.1) | 86 (52.8) | 0.524 |
| Age (years) | 296 | 75 (62–84) [23–101] | 76 (63–84) [32–97] | 74 (60–83) [23–101] | 0.132 |
| Symptom duration at admission (days) | 296 | 4 (2–9) [0–42] | 5 (2–9) [0–21] | 4 (2–9) [0–42] | 0.386 |
| Clinical frailty score | 294 | 4 (2–6) [1–9] | 5 (2–6) [1–9] | 4 (2–6) [1–7] | 0.103 |
| Nursing / residential home | 296 | 60 (20.3) | 33 (24.8) | 27 (16.6) | 0.107 |
| WHO severe COVID-19 at admission | 293 | 131 (44.7) | 86 / 131 (65.6) | 45 / 162 (27.7) | <0.001 |
| CURB-65 score at admission | 287 | 2 (1–2) (0–4) | 2 (1–3) [0–4] | 1 (1–2) [0–4] | 0.003 |
| Pneumonia on admission chest radiograph | 288 | 114 (39.6) | 71 / 132 (53.8) | 43 / 156 (27.6) | 0.004 |
| Cumulative admission duration (days) | 296 | 8 (4–14) [0–28] | 9 (5–18) [0–28] | 8 (3–12) [0–28] | 0.011 |
| Baseline NEWS2 score | 296 | 5 (2–7) [0–16] | 6 (4–8) [0–16] | 3 (2–5) [0–11] | <0.001 |
| Baseline MEWS score | 296 | 2 (1–3) [0–9] | 3 (2–4) [0–9] | 2 (1–3) [0–9] | <0.001 |
| Baseline qSOFA score | 296 | 1 (0–1) [0–3] | 1 (0–1) [0–3] | 0 (0–1) [0–2] | <0.001 |
Data are median (IQR) [range] for continuous variables, and n (%) or n/N (%) for categorical variables.