Box 1.

Types of research needed

Discovery science (understanding infectious organisms, their behaviours and impacts on humans, animals, crops and the environment) to find trends of antimicrobial consumption and antimicrobial resistance.
Drivers and transmission of antimicrobial resistance, including understanding of ‘spillover’, within and between populations, communities or settings, and between humans, animals and the environment.
Innovation (including new treatments, diagnostics, vaccines) and prevention methods (such as infection prevention and control).
Clinical research (such as defining optimal dosages and treatment length) and the role of combination treatments.
Learning to maintain ‘clean’ environments (including sewage and manufacturing effluent).
Behavioural understanding to assess the impact of interventions to mitigate antimicrobial resistance, including for effective ‘stewardship’, communication with patients and the language used to frame and discuss ‘antimicrobial resistance’ or ‘drug-resistant infections’.
Implementation and policy research in order to provide local, national and global policy-makers with the evidence and recommendations needed to guide effective actions.