Laboratory results
| Investigation | Result (normal range) | Comment |
|---|---|---|
| Serum corrected calcium, mmol/L | 2.32 (2.1–2.6) | |
| C-reactive protein, mg/L | 2 (<10) | |
| Plasma glucose (random), mmol/L | 14 (4.1–11) | |
| B12, μg/L | 422 (180–1,000) | |
| Folate, μg/L | 9.9 (>4.0) | |
| Copper, μmol/L | 14.4 (12–25) | |
| Vitamin 25(OH) D, nmol/L | 27.1 (deficiency <30) | |
| Hepatitis B surface antibody, mIU/L | <10 | |
| Hepatitis B surface antigen | Not detected | |
| Hepatitis B core antigen | Not detected | |
| Hepatitis C antibody | Not detected | |
| Syphilis antibody | Not detected | |
| HTLV 1 and 2 antibodies | Not detected | |
| Borrelia burgdorferi immunoglobulin M and G | Not detected | |
| Human herpes virus 6 PCR | Negative | |
| HIV antibody/antigen | Not detected | |
| Mycoplasma pneumoniae complement fixation test | <16 | No significant titres |
| Mycoplasma agg | Negative | |
| Anti-AQP-4 antibody | Negative | |
| Anti-Hu antibody | Negative | |
| Purkinje cell (anti-Yo) antibody | Negative | |
| Anti-Ri antibody | Negative | |
| Anti-MOG antibody | Negative | |
| CSF protein, g/L | 1.62 (0.15–0.4) | |
| CSF glucose, mmol/L | 7.6 | |
| CSF white blood cells, × 10 6/L | 11 | 100% lymphocytes |
| CSF red blood cells, × 10 6/L | 40 | |
| CSF microscopy and culture | No organisms seen, no growth | |
| CSF cytology | No malignant cells seen | |
| CSF JC virus PCR | Negative | |
| CSF oligoclonal bands | Oligoclonal bands of identical band pattern to that found in the serum | Suggestive of a systemic inflammatory response but not of intrathecal immunoglobulin G synthesis |
| Atypical ANCA | Positive | Of doubtful significance |
| PR3 and MPO specific ANCA | Negative | |
| ANA | Negative | |
| ENA (Ro, La, Am, RNP, Scl-70 and Jo-1) | Negative | |
| Serum ACE, U/L | 44 (8–52) |
ACE = angiotensin converting enzyme; ANA = antinuclear antibodies; ANCA = anti-neutrophil cytoplasmic antibodies; AQP-4 = aquaporin-4; CSF = cerebrospinal fluid; ENA = extractable nuclear antigens; HTLV = human T-lymphotropic virus; JC = John Cunningham; MOG = myelin oligodendrocyte glycoprotein; MPO = myeloperoxidase; PCR = polymerase chain reaction.