Finding | Frequency, n (%) | CNS cancer, n | PPV, % (95% CI) | NPV, % (95% CI) |
---|---|---|---|---|
Abnormal | 59 (38.6) | 3 | 5.1 (4.2–6.1) | 100.0 |
Ataxia | 13 (8.5) | 0 | 0.0 | 97.6 (97.4–97.7) |
Sensory disturbance | 8 (5.2) | 0 | 0.0 | 97.7 (97.6–97.8) |
Cranial nerve palsy | 6 (3.9) | 1 | 16.7 (3.2–55.2) | 98.5 (96.7–99.3) |
Hemiparesis | 6 (3.9) | 0 | 0.0 | 100.0 |
Visual field defect | 6 (3.9) | 1 | 16.7 (7.8–32.1) | 100.0 |
CNS = central nervous system; NPV = negative predictive value; PPV = positive predictive value. Of the 59 patients with abnormal examinations, 20 patients had abnormalities from other pre-existing diagnoses, which were not considered relevant to the 2-week wait presentation.