Table 5.

Comparison of our series with two other large series of patients with pneumothorax

Udwadia et alMartinelli et al 10Miro et al 11
Setting3 Mumbai ICUs16 UK hospitals61 Spanish emergency departments
N1,324 critical COVID-19 patientsCase series of 71 patients71,904 all COVID-19 patients
Incidence42/1,324 = 3.17%NA40/71,904 = 0.56%
Age60 (39–83) years21–80 years66 (47–74) years
Male37/42 (88.09%)57/71 (80%)29/40 (72.5%)
Prior lung disease5/42 (12%)28/71 (39.4%)12/40 (30%)
Ventilator-associated alveolar leakVentilator-associated 28/42 (67%)Possibly ventilator-associated 38/61 (62%)NA
Pneumothorax alone18/42 (43%)54/71 (76%)34/40 (85%)
Pneumomediastinium alone16/42 (38%)11/71 (15.5%)NA
Pneumothorax + pneumomediastinum8/42 (19%)6/71 (8.5%)6/40 (15%)
TreatmentObservation 14/42 (33%)Observation 26/71 (36%)Pleural tube 29/40 (73%)
Pleural drain 28/42 (66%)Pleural drain 43/71 (60%)
VATS 1/42 (2%)Surgery 1/71 (1.4%)
Palliative 3/71 (4.2%)
OutcomeDeath 31/42 (73%)Pneumothorax 63.1±6.5%NA
Pneumomediastinum 53.0±18.7%