Causes of false positive troponin results versus true positives unrelated to myocardial infarction
| False positive causes | True raise in troponin not related to myocardial infarction |
|---|---|
| High alkaline phosphatase | Myocarditis/pericarditis |
| Fibrin clots | Pulmonary embolism |
| Haemolysis | Congestive heart failure |
| Heterophile antibody interference | Arrhythmias |
| Microparticles in specimen sample | Chronic kidney disease |
| Immunocomplex formation | Cardiac surgery |
| Rheumatoid factor | Cardiac procedures: ablation, cardioversion and primary percutaneous coronary intervention |
| Auto-antibodies | Critical illness |
| Interfering endogenous components in blood eg bilirubin, haemoglobin and lipaemia | Severe anaemia |
| Inflammatory conditions |