Maximal clinical and systemic inflammatory responses stratified by age
| Age range, years | Temperature, °C | Maximum serum CRP, mg/L | Maximum systolic BP, mmHg | Maximum diastolic BP, mmHg | Maximum pulse, bpm | Maximum blood neutrophils, × 109/L |
|---|---|---|---|---|---|---|
| 0–9 | 37.1 (36.8–37.4) n = 28 | 23.1 (8.9–37.4) n = 22 | 99.8 (94.8–104.7) n = 25 | 62.2 (57.4–66.9) n = 25 | 136.4 (125.0–147.8) n = 28 | 3.8 (2.7–4.8) n = 24 |
| 10–19 | 37.2 (37–37.4) n = 63 | 32.4 (17.3–47.6) n = 51 | 122.4 (117.4–127.5) n = 60 | 71.8 (66.9–76.7) n = 60 | 91.7 (86.2–97.3) n = 63 | 4.7 (3.9–5.5) n = 58 |
| 20–29 | 37.2 (37–37.3) n = 123 | 34.5 (22–47) n = 95 | 128.5 (124.5–132.4) n = 91 | 75.7 (73.1–78.3) n = 91 | 95 (91.2–98.8) n = 121 | 5.7 (5.2–6.3) n = 121 |
| 30–39 | 37.3 (37.1–37.4) n = 165 | 36.5 (25.7–47.4) n = 147 | 132.7 (129.2–136.3) n = 143 | 80.1 (77.8–82.4) n = 143 | 94.2 (90.9–97.5) n = 165 | 5.4 (4.9–5.8) n = 162 |
| 40–49 | 37.3 (37.2–37.4) n = 251 | 47.3 (37.6–57) n = 245 | 138 (134.9–141.1) n = 251 | 82.2 (80.4–84.1) n = 251 | 94.8 (92.3–97.2) n = 251 | 5.5 (5.0–5.9) n = 255 |
| 50–59 | 37.2 (37.1–37.3) n = 409 | 52.8 (44.3–61.4) n = 392 | 139.2 (136.8–141.7) n = 409 | 80.8 (79.3–82.2) n = 409 | 94.1 (92.1–96) n = 409 | 6.2 (5.7–6.7) n = 410 |
| 60–69 | 37.1 (37.1–37.2) n = 468 | 79.2 (69.9–88.5) n = 460 | 140.5 (137.7–143.3) n = 468 | 79.3 (77.7–80.9) n = 468 | 93.7 (91.8–95.5) n = 468 | 6.9 (6.4–7.4) n = 475 |
| 70–79 | 37.1 (37–37.1) n = 813 | 68.8 (63.0–74.5) n = 797 | 142.5 (140.4–144.6) n = 813 | 78.7 (77.4–79.9) n = 813 | 92.2 (90.8–93.6) n = 813 | 6.9 (6.6–7.2) n = 813 |
| 80–89 | 36.9 (36.9–37) n = 971 | 77.6 (72.0–83.2) n = 956 | 143.6 (141.5–145.7) n = 971 | 77.5 (76.3–78.7) n = 971 | 90.8 (89.5–92.0) n = 972 | 6.9 (6.7–7.2) n = 970 |
| 90–99 | 36.8 (36.8–36.9) n = 278 | 74.2 (64.6–83.8) n = 267 | 142.7 (138.7–146.6) n = 278 | 75.5 (73.3–77.7) n = 278 | 87.7 (85–90.4) n = 278 | 7.2 (6.6–7.7) n = 275 |
| p value (oneway ANOVA) | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
Values in cells = mean maximum values (95% confidence interval), n = number of patients with one or more measurements. BP = blood pressure; CRP = C-reactive protein.