Recommendations for medical management of coronary artery disease | Relevant treatment targets |
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All patients with coronary artery disease should be initiated on high-dose statin treatment, such as atorvastatin 80 mg once nightly, irrespective of their formal lipid profile results. | Aim to decrease LDL-C by at least 50% of the patient's baseline with an overall target for total LDL-C of <1.4 mmol/L.11,24 |
Angiotensin-converting enzyme inhibitors are recommended for all patients with co-existing diabetes, chronic kidney disease or heart failure with an ejection fraction <40%. | Aim to target blood pressure of <140/90 mmHg or ideally <130/80 mmHg if the patient is able to tolerate this.11,24 |
All patients with co-existing diabetics should have their diabetic control optimised. | Aim to target glycated haemoglobin <53 mmol/mol, however, more stringent goals may be chosen for selected patients.24 |
LDL-C = low-density lipoprotein cholesterol.