Table 4.

Clinical course and outcomes of patients who were critically ill with COVID-19 with and without heparin-induced thrombocytopenia

No HIT, n=91HIT, n=16p-value
Mechanically ventilated, n (%)69 (75.8)16 (100.0)0.061
Thrombosis, n (%)9 (9.9)3 (18.8)0.544
Bleeding, n (%)36 (39.6)12 (75.0)0.018
Blood products, n (%)46 (50.5)16 (100.0)0.001
PLT, n (%)4 (4.4)9 (56.2)<0.001
FFP, n (%)10 (11.0)5 (31.2)0.078
Cryo, n (%)4 (4.4)3 (18.8)0.111
ECS, n (%)23 (25.3)16 (100.0)<0.001
ECMO, n (%)8 (8.8)14 (87.5)<0.001
CVVH, n (%)22 (24.2)9 (56.2)0.021
Dialysis, n (%)6 (6.6)4 (25.0)0.062
LOS, days, median (IQR)21.00 (12.00–37.50)31.50 (21.25–53.25)0.026
Mortality, n (%)37 (40.7)11 (68.8)0.070
  • Cryo = cryoprecipitate; CVVH = continuous venous-venous hemofiltration; DIC = disseminated intravascular coagulopathy; ECMO = extracorporeal membrane oxygenation; ECS = extracorporeal support; FFP = fresh frozen plasma; HIT = heparin-induced thrombocytopenia; IQR = interquartile range; LOS = length of stay; PLT = platelets.