Table 1.

Summary of investigations results during early phase of admission

Investigations	Case 1	Case 2	Reference range
Homocysteine total	Not done	58.2 umol/l	0–15 umol/l
Active B12	36	63 pmol/L	25–108 pmol/L <25: B12 deficiency 25–70: possible B12 deficiency >70: B12 depleted
Methylmalonic acid	11,427	675 nmol/L	0–280 nmol/L High level suggests functional vitamin B12 deficiency at the tissue level
Anti-phospholipid syndrome screen	Negative	Negative
Protein C activity	114.1 iu/dL	121.9 iu/dL	81.1–146.3 iu/dL
Free protein S antigen	116.6 iu/dL	Not done iu/dL	80.2–137.4 iu/dL
Anti-thrombin activity	51.6 iu/dL	107.2 iu/dL	87–124.5 iu/dL
Prothrombin 20210	Normal	Normal
Factor V Leiden	Not done	Normal
JAK2 V617F	Not detected	Not done