Clinical indicator diseases for adult HIV infection.
| AIDS-defining condition | Other conditions where HIV testing should be offered | |
|---|---|---|
| Respiratory | Tuberculosis Pneumocystis | Bacterial pneumonia Aspergillosis |
| Neurology | Cerebral toxoplasmosis Primary cerebral lymphoma Cryptococcal meningitis Progressive multifocal leucoencephalopathy | Aseptic meningitis/encephalitis Cerebral abscess Space occupying lesion of unknown cause Guillain–Barré syndrome Transverse myelitis Peripheral neuropathy Dementia Leucoencephalopathy |
| Dermatology | Kaposi's sarcoma | Severe or recalcitrant seborrhoeic dermatitis Severe or recalcitrant psoriasis Multidermatomal or recurrent herpes zoster |
| Gastroenterology | Persistent cryptosporidiosis | Oral candidiasis Oral hairy leukoplakia Chronic diarrhoea of unknown cause Weight loss of unknown cause Salmonella, shigella or campylobacter Hepatitis B infection Hepatitis C infection |
| Oncology | Non-Hodgkin's lymphoma | Anal cancer or anal intraepithelial dysplasia Lung cancer Seminoma Head and neck cancer Hodgkin's lymphoma Castleman's disease |
| Gynaecology | Cervical cancer | Vaginal intraepithelial neoplasia Cervical intraepithelial neoplasia grade 2 or above |
| Haematology | Any unexplained blood dyscrasia including neutropenia, thrombocytopenia or lymphopenia | |
| Ophthalmology | Cytomegalovirus retinitis | Infective retinal diseases including herpes viruses and toxoplasma Any unexplained retinopathy |
| Ear, nose and throat | Lymphadenopathy of unknown cause Chronic parotitis Lymphoepithelial parotid cysts | |
| Other | Pyrexia of unknown origin Any lymphadenopathy of unknown cause Mononucleosis-like syndrome (primary HIV infection) Any sexually transmitted infection |
STI = sexually transmitted infection.